I've been experimenting with Joomla, and open source content management system, and have found it to be a powerful tool. As part of the experiment, I have modified existing templates to create a custom look, and then have redesigned two existing sites with the program. Here are the new sites. Both are completely user-editable through a browser-based interface, and there is no loss in design.
The Desert Institute for Spine Care
Bergen Pain Management (uses JoomFish for multi-language pages)

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